Invention Grant
- Patent Title: Mimetics of sulfated oligosaccharides
- Patent Title (中): 硫酸低聚糖的模拟物
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Application No.: US13056085Application Date: 2009-07-09
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Publication No.: US08853387B2Publication Date: 2014-10-07
- Inventor: Giangiacomo Torri , Elena Vismara , Israel Vlodavsky , Annamaria Naggi
- Applicant: Giangiacomo Torri , Elena Vismara , Israel Vlodavsky , Annamaria Naggi
- Applicant Address: IT Milan
- Assignee: Istituto di Ricerche Chimiche e Biochimiche “G. Ronzoni”
- Current Assignee: Istituto di Ricerche Chimiche e Biochimiche “G. Ronzoni”
- Current Assignee Address: IT Milan
- Priority: EP08160464 20080715
- International Application: PCT/EP2009/058742 WO 20090709
- International Announcement: WO2010/006982 WO 20100121
- Main IPC: C07H11/00
- IPC: C07H11/00 ; C07H17/04 ; C07H5/10
Abstract:
The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C—C bond, and wherein the sulfation degree expressed as percentage of OH groups substituted by a OSO3− group is comprised between 50 and 100%. The sulfated oligosaccharides according to the invention are useful as a drug, in particular in the treatment of angiogenesis, metastasis, and inflammation.
Public/Granted literature
- US20120232263A1 Mimetics of Sulfated Oligosaccharides Public/Granted day:2012-09-13
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