Invention Grant
US08853412B2 Pyrrolidinone derivatives as GPR119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
有权
吡咯烷酮衍生物作为治疗糖尿病，肥胖，血脂异常和相关疾病的GPR119调节剂
- Patent Title: Pyrrolidinone derivatives as GPR119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
- Patent Title (中): 吡咯烷酮衍生物作为治疗糖尿病，肥胖，血脂异常和相关疾病的GPR119调节剂
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Application No.: US14048425Application Date: 2013-10-08
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Publication No.: US08853412B2Publication Date: 2014-10-07
- Inventor: Lothar Schwink , Martin Bossart , Heiner Glombik , Matthias Gossel , Dieter Kadereit , Thomas Klabunde , Thomas Maier , Siegfried Stengelin
- Applicant: Lothar Schwink , Martin Bossart , Heiner Glombik , Matthias Gossel , Dieter Kadereit , Thomas Klabunde , Thomas Maier , Siegfried Stengelin
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP12306231 20121009
- Main IPC: C07D401/00
- IPC: C07D401/00 ; A61K31/44 ; A61K31/497 ; C07D401/12 ; A61K31/4545 ; C07D413/14 ; A61K31/4439 ; C07D401/14 ; C07D407/14 ; C07D417/14 ; C07D207/12 ; C07D405/14 ; A61K31/444 ; A61K31/4015
Abstract:
The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
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