Invention Grant
US08853429B2 Process and intermediate compounds useful in the preparation of statins
有权
用于制备他汀类药物的方法和中间体化合物
- Patent Title: Process and intermediate compounds useful in the preparation of statins
- Patent Title (中): 用于制备他汀类药物的方法和中间体化合物
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Application No.: US13951650Application Date: 2013-07-26
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Publication No.: US08853429B2Publication Date: 2014-10-07
- Inventor: David John Moody , Jonathan William Wiffen
- Applicant: Redx Pharma Limited
- Applicant Address: GB
- Assignee: Redx Pharma Limited
- Current Assignee: Redx Pharma Limited
- Current Assignee Address: GB
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Priority: GB0427491.6 20041216
- Main IPC: C07D215/38
- IPC: C07D215/38 ; C07D405/06 ; C07D257/04 ; C07D309/30 ; C07D209/24 ; C07C51/09 ; C07D309/10 ; C07D215/14 ; C07B41/08

Abstract:
There is provides a process for the preparation of a compound of formula (7): wherein R is an optionally substituted hydrocarbyl group or an optionally substituted heterocyclic group; provides that R is not a compound of Formula (a): wherein Ra represents an alkyl group, such as a C1-16 alkyl group, and preferably an isopropyl group; Rb represents an aryl group, preferably a 4-fluorophenyl group; Rc represents hydrogen, a protecting group or an alkyl group, such as a C1-16 alkyl group, and preferably a methyl group; and Rd represents hydrogen, a protecting group or a SO2Re group where Re is an alkyl group, such as a C1-16 alkyl group, and preferably a methyl group.
Public/Granted literature
- US20130345429A1 PROCESS AND INTERMEDIATE COMPOUNDS USEFUL IN THE PREPARATION OF STATINS Public/Granted day:2013-12-26
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