Invention Grant
- Patent Title: Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum
- Patent Title (中): 将激光喷射电离质谱概念从大气压力扩展到真空的系统和方法
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Application No.: US13881684Application Date: 2011-10-25
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Publication No.: US08853621B2Publication Date: 2014-10-07
- Inventor: Sarah Trimpin
- Applicant: Sarah Trimpin
- Applicant Address: US MI Detriot
- Assignee: Wayne State University
- Current Assignee: Wayne State University
- Current Assignee Address: US MI Detriot
- Agency: Lee & Hayes, PLLC
- Agent C. Rachal Winger
- International Application: PCT/US2011/057769 WO 20111025
- International Announcement: WO2012/058248 WO 20120503
- Main IPC: H01J49/40
- IPC: H01J49/40 ; H01J49/06 ; H01J49/00 ; B01D59/44 ; G01N27/62

Abstract:
Disclosed herein are systems and methods that allow analysis of macromolecular structures using laserspray ionization at intermediate pressure or high vacuum using commercially available mass spectrometers with or without modification and with the application of heat. The systems and methods produce multiply-charged ions for improved analysis in mass spectrometry.
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