The present invention discloses a high efficiency constant current LED driver, which comprises a rectification bridge, a PFC main circuit, an isolated DC/DC converter, a PFC controller and a PFC bus control circuit. Since the input voltage is an intermediate PFC bus voltage, which varies with the output voltage of the DC/DC converter. When the isolated DC/DC converter is an LLC resonant circuit, the operating frequency of the LLC circuit is close to the resonant frequency within a wide output voltage range. Thus, the gain range and the operating frequency is narrow, and can enable the constant current module to work with a high efficiency at a wide output voltage range. When the isolated DC/DC converter is a symmetric half bridge, or an asymmetric half bridge or a full bridge circuit, the duty cycle of DC/DC circuit is close to 50% within a wide output voltage range. Thus, the changing range of the duty cycle of the DC/DC converter will be narrow and can improve the efficiency dramatically.