A three-dimensional integrated circuit (3-D IC) includes a controller chip and at least one memory chip, in which, besides an original storage capacity, the memory chip further includes multiple spare memory cells and an address translation circuit with an external activation/enablement function. After the memory chip and the controller chip are stacked, the controller chip may still activate/enable a spare in the memory chip to repair a damaged or deteriorated memory cell in the memory chip through at least one vertical interconnect (for example, through-silicon via (TSV)), regardless of whether the damaged or deteriorated memory cell has been repaired or not before the controller chip and the memory chip are stacked.