Disclosed are methods and apparatus for interference cancellation in a wireless communication system. In particular, the disclosed methods and apparatus provide for interference cancellation in a wireless device, including extending linear interference cancellation techniques, such as quasi-linear interference cancellation (QLIC), in the wireless device to a first orthogonal set, which may be a first quasi orthogonal function (QOF) set for a cdma2000 system to cancel interference from that set upon another desired QOF set. QLIC may also be extended to cancellation of signals from non-intended base stations as well. Accordingly, the present methods and apparatus afford reduced interference through QLIC by canceling signals due to either undesired QOF sets or non-intended base stations, which in turn results in an increase in forward link capacity.