Certain embodiments herein may include systems and methods for facilitating communication between mobile devices and display devices. According to certain embodiments, various types of connections may be established for communication between mobile devices and display devices. The type of connection may be based on numerous factors, including networks accessible to the mobile devices and display devices, capabilities of the mobile devices and display devices, and requirements associated with a software application running on a display device or on a device associated with the display device. Example connection types may involve a server intermediary which may establish a communication connection and proxy or relay content between mobile devices and display devices. Other connection types may not involve a server intermediary, for example, when a mobile device interacts with a display device to control a real-time game application.