Aspects of the invention relate to systems and methods for securely retaining profile data and the use of such data for the targeted delivery of content. In one embodiment, a unique profile that represents the user location and is keyed to profile attributes selected from both a first set of data collected from the user location and the second set of profile data collected from an external source, is generated. The key does not allow a third party to identify the end-user location or a user associated with the end-user location. Electronic content transmitted to end-user locations may be encoded such that it may only be accessed by an authorized user and/or on a specific electronic device at the user location. A graphical user interface may be utilized to allow a third-party to provide selection criteria for determining user locations to receive targeted content. Further aspects of the invention relate to an electronic device configured to present targeted content to a user at a user location.