发明授权
US08859572B2 Sulfone substituted 2,3-dihydroimidazo [1,2-C] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis
有权
用于治疗高增殖性疾病和血管生成疾病的砜取代的2,3-二氢咪唑并[1,2-C]喹唑啉衍生物
![Sulfone substituted 2,3-dihydroimidazo [1,2-C] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis](/docs/US/2014-10-14/US08859572B2/abs.jpg.600x600.jpg)
- 专利标题： Sulfone substituted 2,3-dihydroimidazo [1,2-C] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis
- 专利标题（中）： 用于治疗高增殖性疾病和血管生成疾病的砜取代的2,3-二氢咪唑并[1,2-C]喹唑啉衍生物
-
申请号： US12812911申请日： 2009-01-13
-
公开(公告)号： US08859572B2公开(公告)日： 2014-10-14
- 发明人: Martin F. Hentemann , William Scott , Jill Wood , Jeffrey Johnson , Aniko Redman , Ann-Marie Bullion , Leatte Guernon
- 申请人： Martin F. Hentemann , William Scott , Jill Wood , Jeffrey Johnson , Aniko Redman , Ann-Marie Bullion , Leatte Guernon
- 申请人地址： DE Monheim
- 专利权人： Bayer Intellectual Property GmbH
- 当前专利权人： Bayer Intellectual Property GmbH
- 当前专利权人地址： DE Monheim
- 国际申请： PCT/US2009/000228 WO 20090113
- 国际公布： WO2009/091550 WO 20090723
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K45/06 ; A61K31/541 ; C07D487/04
![Sulfone substituted 2,3-dihydroimidazo [1,2-C] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis](/abs-image/US/2014/10/14/US08859572B2/abs.jpg.150x150.jpg)
摘要：
This invention relates to novel sulfone 2I3-dihydroimidazo[1 l2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis mediated disorders, as a sole agent or in combination with other active ingredients.
公开/授权文献
信息查询
IPC分类:
