Invention Grant
US08859573B2 Pyrimidinone and pyridinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
有权
嘧啶酮和吡啶酮化合物，用于治疗由Lp-PLA2介导的疾病或病症
- Patent Title: Pyrimidinone and pyridinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
- Patent Title (中): 嘧啶酮和吡啶酮化合物，用于治疗由Lp-PLA2介导的疾病或病症
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Application No.: US13991953Application Date: 2011-12-05
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Publication No.: US08859573B2Publication Date: 2014-10-14
- Inventor: Zehong Wan , Xiaomin Zhang , Jian Wang , Cheng Peng , Yun Jin , Yimin Hu
- Applicant: Zehong Wan , Xiaomin Zhang , Jian Wang , Cheng Peng , Yun Jin , Yimin Hu
- Applicant Address: GB Brentford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Fang Qian
- Priority: WOPCT/CN2010/079463 20101206
- International Application: PCT/CN2011/083465 WO 20111205
- International Announcement: WO2012/075917 WO 20120614
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D401/06 ; C07D403/06 ; C07D401/14 ; C07D213/69 ; C07D239/52 ; C07D401/12
Abstract:
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.
Public/Granted literature
- US20130252986A1 COMPOUNDS Public/Granted day:2013-09-26
Information query
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