发明授权
- 专利标题: Amino triazoles as PI3K inhibitors
- 专利标题(中): 氨基三唑作为PI3K抑制剂
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申请号: US12744940申请日: 2008-11-21
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公开(公告)号: US08865699B2公开(公告)日: 2014-10-21
- 发明人: Nigel Ramsden , Kathryn Bell , Andrew David Cansfield , Jess Taylor , Mihiro Sunose , David Middlemiss , Gitte Neubauer
- 申请人: Nigel Ramsden , Kathryn Bell , Andrew David Cansfield , Jess Taylor , Mihiro Sunose , David Middlemiss , Gitte Neubauer
- 申请人地址: GB Brentford, Middlesex
- 专利权人: Cellzome Ltd.
- 当前专利权人: Cellzome Ltd.
- 当前专利权人地址: GB Brentford, Middlesex
- 代理商 Loretta J. Sauermelch; Alan X. Scrivner
- 优先权: EP07121607 20071127
- 国际申请: PCT/EP2008/066001 WO 20081121
- 国际公布: WO2009/068482 WO 20090604
- 主分类号: A01N43/42
- IPC分类号: A01N43/42 ; A61K31/44 ; C07D471/02 ; C07D491/02 ; C07D498/02
摘要:
The invention relates to compounds of formula (I) wherein X, T1 and R1 to R3 have the meaning as cited in the description and the claims. Said compounds are useful as protein kinase inhibitors, especially inhibitors of PI3K, for the treatment or prophylaxis of immunological, inflammatory, autoimmune, or allergic disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the production of and use as medicaments.
公开/授权文献
- US20110021497A1 AMINO TRIAZOLES AS PI3K INHIBITORS 公开/授权日:2011-01-27