发明授权
US08865738B2 5-membered heterocyclic compound cyclopenta[C]pyrrolylalkylcarbamate derivatives, preparation thereof, and therapeutic use thereof
有权
5元杂环化合物环戊二烯并[C]吡咯基烷基氨基甲酸酯衍生物及其治疗用途
![5-membered heterocyclic compound cyclopenta[C]pyrrolylalkylcarbamate derivatives, preparation thereof, and therapeutic use thereof](/docs/US/2014-10-21/US08865738B2/abs.jpg.600x600.jpg)
- 专利标题： 5-membered heterocyclic compound cyclopenta[C]pyrrolylalkylcarbamate derivatives, preparation thereof, and therapeutic use thereof
- 专利标题（中）： 5元杂环化合物环戊二烯并[C]吡咯基烷基氨基甲酸酯衍生物及其治疗用途
-
申请号： US13319635申请日： 2010-05-11
-
公开(公告)号： US08865738B2公开(公告)日： 2014-10-21
- 发明人: Ahmed Abouabdellah , Aude Fayol , Alistair Lochead , Mourad Saady , Julien Vache , Philippe Yaiche
- 申请人： Ahmed Abouabdellah , Aude Fayol , Alistair Lochead , Mourad Saady , Julien Vache , Philippe Yaiche
- 申请人地址： FR Paris
- 专利权人： Sanofi
- 当前专利权人： Sanofi
- 当前专利权人地址： FR Paris
- 代理机构： Scully, Scott, Murphy & Presser P.C.
- 优先权： FR0902267 20090512
- 国际申请： PCT/FR2010/050912 WO 20100511
- 国际公布： WO2010/130943 WO 20101118
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D261/10 ; C07D277/22 ; C07D231/12 ; C07D401/14
![5-membered heterocyclic compound cyclopenta[C]pyrrolylalkylcarbamate derivatives, preparation thereof, and therapeutic use thereof](/abs-image/US/2014/10/21/US08865738B2/abs.jpg.150x150.jpg)
摘要：
The invention relates to compounds of the general formula (I) where: R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy, or NR8R9 group; m and p have a value of 1; n and o have the same value which is 0 or 1; A is a covalent bond or a C1-8-alkylene group; R1 is an optionally substituted aryl or heteroaryl group; R3 is a hydrogen or fluorine atom or a C1-6-alkyl group or a trifluoromethyl group; R4 is an optionally substituted 5-membered heterocyclic compound; wherein the compounds can be in the state of a base or an acid addition salt. The present invention can be used in therapeutics.
公开/授权文献
信息查询
