发明授权
US08877207B2 Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of Alzheimer's disease and associated methods
有权
靶向阿尔茨海默病淀粉样蛋白β抗原的氧化铈纳米颗粒及相关方法
- 专利标题： Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of Alzheimer's disease and associated methods
- 专利标题（中）： 靶向阿尔茨海默病淀粉样蛋白β抗原的氧化铈纳米颗粒及相关方法
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申请号： US13184660申请日： 2011-07-18
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公开(公告)号： US08877207B2公开(公告)日： 2014-11-04
- 发明人: Annamaria Cimini , Barbara D'Angelo , Soumen Das , Sudipta Seal
- 申请人： Annamaria Cimini , Barbara D'Angelo , Soumen Das , Sudipta Seal
- 申请人地址： US FL Orlando IT L'Aquila, Abruzzo
- 专利权人： University of Central Florida Research Foundation, Inc.,University of l'Aquila
- 当前专利权人： University of Central Florida Research Foundation, Inc.,University of l'Aquila
- 当前专利权人地址： US FL Orlando IT L'Aquila, Abruzzo
- 代理机构： Beusse, Wolter, Sanks & Maire, P.A.
- 代理商 Timothy H. Van Dyke
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K39/385 ; A61K38/00 ; A61K47/48 ; B82Y5/00
摘要：
Disclosed is a composition immunologically targeted to Alzheimer's disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD. The invention also includes a medication manufactured with the targeted nanoceria particles and methods of treatment by administering the targeted nanoceria particles to patients in need thereof.
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