发明授权
- 专利标题： Radiotracer precursor and method for preparing the same
- 专利标题（中）： 放射性示踪剂前体及其制备方法
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申请号： US13609938申请日： 2012-09-11
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公开(公告)号： US08877943B2公开(公告)日： 2014-11-04
- 发明人: Show-Wen Liu , Yu Chang , Cheng-Fang Hsu , Ming-Che Tsai , Tsung-Hsien Chiang , Yueh-Feng Deng , Kuei-Lin Lu , Chih-Yuan Lin , Da-Ming Wang , Ching-Yun Li
- 申请人： Show-Wen Liu , Yu Chang , Cheng-Fang Hsu , Ming-Che Tsai , Tsung-Hsien Chiang , Yueh-Feng Deng , Kuei-Lin Lu , Chih-Yuan Lin , Da-Ming Wang , Ching-Yun Li
- 申请人地址： TW Taoyuan County
- 专利权人： Atomic Energy Council-Institute of Nuclear Eenergy Research
- 当前专利权人： Atomic Energy Council-Institute of Nuclear Eenergy Research
- 当前专利权人地址： TW Taoyuan County
- 代理机构： Rosenberg, Klein & Lee
- 主分类号： C07D207/09
- IPC分类号： C07D207/09
摘要：
A precursor SnBZM for a dopamine receptor radiotracer and a method for preparing the same are revealed. The precursor includes a tributyltin group (Bu3Sn) that is easy to be replaced. Thus a dopamine receptor radiotracer 123I-IBZM can be produced at high yield rate by a substitution reaction of the precursor. At the same time, both the method for preparing the precursor SnBZM and a method for preparing a reference standard IBZM are simplified. Moreover, stability of each product is improved.
公开/授权文献
- US20140073803A1 RADIOTRACER PRECURSOR AND METHOD FOR PREPARING THE SAME 公开/授权日：2014-03-13
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