发明授权
- 专利标题: Method for production of pH stable enveloped viruses
- 专利标题(中): 生产pH稳定包膜病毒的方法
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申请号: US12626475申请日: 2009-11-25
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公开(公告)号: US08883479B2公开(公告)日: 2014-11-11
- 发明人: Brigitte Krenn , Markus Wolschek , Julia Romanova , Andrej Egorov , Sabine Nakowitsch
- 申请人: Brigitte Krenn , Markus Wolschek , Julia Romanova , Andrej Egorov , Sabine Nakowitsch
- 申请人地址: CH Glattpark (Opfikon)
- 专利权人: Baxter Healthcare SA
- 当前专利权人: Baxter Healthcare SA
- 当前专利权人地址: CH Glattpark (Opfikon)
- 代理机构: Loza & Loza, LLP
- 代理商 Michael Fedrick
- 优先权: EP09153664 20090225
- 主分类号: A61K39/145
- IPC分类号: A61K39/145 ; C12N7/00 ; C12N7/01 ; A61K39/00
摘要:
The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.
公开/授权文献
- US20100172934A1 METHOD FOR PRODUCTION OF pH STABLE ENVELOPED VIRUSES 公开/授权日:2010-07-08
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