发明授权
US08883963B2 Peptidomimetics with glucagon antagonistic and GLP 1 agonistic activities
有权
肽模拟物与胰高血糖素拮抗和GLP 1激动活性
- 专利标题: Peptidomimetics with glucagon antagonistic and GLP 1 agonistic activities
- 专利标题(中): 肽模拟物与胰高血糖素拮抗和GLP 1激动活性
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申请号: US12746536申请日: 2008-12-10
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公开(公告)号: US08883963B2公开(公告)日: 2014-11-11
- 发明人: Rajesh H. Bahekar , Mukul R. Jain , Pankaj Ramanbhai Patel
- 申请人: Rajesh H. Bahekar , Mukul R. Jain , Pankaj Ramanbhai Patel
- 申请人地址: IN Ahmedabad, Gujarat
- 专利权人: Cadila Healthcare Limited
- 当前专利权人: Cadila Healthcare Limited
- 当前专利权人地址: IN Ahmedabad, Gujarat
- 代理机构: Ladas & Parry LLP
- 优先权: IN2420/MUM/2007 20071211; IN1696/MUM/2008 20080811
- 国际申请: PCT/IN2008/000831 WO 20081210
- 国际公布: WO2009/125424 WO 20091015
- 主分类号: C07K14/605
- IPC分类号: C07K14/605 ; A61K38/00
摘要:
The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-I receptor agonistic activity.
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