Techniques for adjusting transmit timing of base stations and user equipments (UEs) in a wireless network are described. In one operating scenario, a femto base station communicates with a femto UE, and a macro base station communicates with a macro UE located within the coverage of the femto base station. In an aspect, the transmit timing of the femto base station may be delayed relative to the transmit timing of the macro base station, e.g., to time align downlink signals from the femto and macro base stations at the femto and macro UEs. In another aspect, the transmit timing of the femto UE may be advanced relative to the transmit timing of femto base station by an amount larger than twice the propagation delay between the femto UE and the femto base station, e.g., to time align uplink signals from the femto and macro UEs at the femto base station.