Invention Grant
US08895566B2 5H-cyclopenta[d]pyrimidines as AKT protein kinase inhibitors
有权
5H-环戊二烯并[d]嘧啶作为AKT蛋白激酶抑制剂
![5H-cyclopenta[d]pyrimidines as AKT protein kinase inhibitors](/docs/US/2014-11-25/US08895566B2/abs.jpg.600x600.jpg)
- Patent Title: 5H-cyclopenta[d]pyrimidines as AKT protein kinase inhibitors
- Patent Title (中): 5H-环戊二烯并[d]嘧啶作为AKT蛋白激酶抑制剂
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Application No.: US13678395Application Date: 2012-11-15
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Publication No.: US08895566B2Publication Date: 2014-11-25
- Inventor: Anna Banka , Josef R. Bencsik , James F. Blake , Martin F. Hentemann , Nicholas C. Kallan , Jun Liang , Ian S. Mitchell , Stephen T. Schlachter , Eli M. Wallace , Rui Xu , Tony P. Tang
- Applicant: Array BioPharma Inc. , Genentech, Inc.
- Applicant Address: US CO Boulder US CA South San Francisco
- Assignee: Array Biopharma Inc.,Genetech, Inc.
- Current Assignee: Array Biopharma Inc.,Genetech, Inc.
- Current Assignee Address: US CO Boulder US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D403/10 ; C07D409/04 ; C07D239/70 ; C07D401/04 ; C07D403/04 ; C07D487/04 ; C07D401/12 ; C07D417/10 ; C07D401/10 ; C07D417/04
![5H-cyclopenta[d]pyrimidines as AKT protein kinase inhibitors](/abs-image/US/2014/11/25/US08895566B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Public/Granted literature
- US20130085135A1 5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS Public/Granted day:2013-04-04
Information query
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