A method for controlling the operation of a wind farm with a plurality of wind turbines is disclosed A setpoint vector is defined, wherein each component of the setpoint vector represents an individual power setpoint of one of the plurality of wind turbines. A dependency matrix, which reflects a desired power generation distribution between different wind turbines of the plurality of wind turbines, is determined. A power reference vector is calculated by multiplying the dependency matrix with the setpoint vector, such that the power reference vector comprises a coordinated power setpoint for each wind turbine. The operation of the wind farm is controlled based on the calculated power reference vector. A superordinate control system, a wind farm, a computer-readable medium and a program element, which are adapted for performing and/or for controlling the above described wind farm operation control method are further disclosed.