发明授权
US08900589B2 Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
有权
蒽环类衍生物缀合物，其制备方法及其作为抗肿瘤化合物的用途
- 专利标题： Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
- 专利标题（中）： 蒽环类衍生物缀合物，其制备方法及其作为抗肿瘤化合物的用途
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申请号： US12502433申请日： 2009-07-14
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公开(公告)号： US08900589B2公开(公告)日： 2014-12-02
- 发明人: Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
- 申请人： Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
- 申请人地址： US CA South San Francisco
- 专利权人： Genetech, Inc.
- 当前专利权人： Genetech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Genetech, Inc.
- 代理商 Alex Andrus
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; A61K39/00 ; C07K16/28 ; C07K14/00
摘要：
The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
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