发明授权
- 专利标题： Haemophilus parasuis polypeptides and methods of use
- 专利标题（中）： 嗜血杆菌多肽和使用方法
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申请号： US13508225申请日： 2010-11-04
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公开(公告)号： US08911743B2公开(公告)日： 2014-12-16
- 发明人: Simone Oliveira
- 申请人： Simone Oliveira
- 申请人地址： US MN Saint Paul
- 专利权人： Regents of the University of Minnesota
- 当前专利权人： Regents of the University of Minnesota
- 当前专利权人地址： US MN Saint Paul
- 代理机构： Mueting, Raasch & Gebhardt, P.A.
- 国际申请： PCT/US2010/055425 WO 20101104
- 国际公布： WO2011/056954 WO 20110512
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/102 ; C07K1/00 ; G01N33/569 ; C07K14/285
摘要：
The present invention provides isolated polypeptides having oligopeptide permease activity and an amino acid sequence that has at least 80% identity with a Haemophilus parasuis OppA polypeptide. Also provided by the present invention are isolated polynucleotides that encode the polypeptides described herein, and antibody that specifically binds a polypeptide described herein. The present invention further provides genetically modified microbes, such as attenuated Haemophilus parasuis strains and other microbes that express polypeptides described herein. Also included are methods for using the polypeptides, polynucleotides, antibody, and genetically modified microbes.
公开/授权文献
- US20130129682A1 HAEMOPHILUS PARASUIS POLYPEPTIDES AND METHODS OF USE 公开/授权日：2013-05-23