发明授权
US08920803B2 Immunotherapeutic method involving CD123 (IL-3Rα) antibodies and immunostimulating complex
有权
涉及CD123(IL-3Rα)抗体和免疫刺激复合物的免疫治疗方法
- 专利标题: Immunotherapeutic method involving CD123 (IL-3Rα) antibodies and immunostimulating complex
- 专利标题(中): 涉及CD123(IL-3Rα)抗体和免疫刺激复合物的免疫治疗方法
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申请号: US13704583申请日: 2011-06-15
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公开(公告)号: US08920803B2公开(公告)日: 2014-12-30
- 发明人: Debra Pauline Drane , Eugene Maraskovsky , Jefferey Stephen Boyle
- 申请人: Debra Pauline Drane , Eugene Maraskovsky , Jefferey Stephen Boyle
- 申请人地址: AU Parkville
- 专利权人: CSL Limited
- 当前专利权人: CSL Limited
- 当前专利权人地址: AU Parkville
- 代理机构: Cooley LLP
- 国际申请: PCT/AU2011/000725 WO 20110615
- 国际公布: WO2011/156860 WO 20111222
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K39/395 ; C12P21/08 ; C07K16/28 ; C07K16/30
摘要:
A method for the treatment of a condition which is characterized by CD 123-expressing cells in a patient comprises administering to the patient (i) an antibody or antibody fragment which binds selectively to IL-3Rα(CD 123), and (ii) an immunostimulating complex which comprises saponin, a sterol and a phospholipid.
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