发明授权
US08921052B2 Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method
有权
血红蛋白衍生物测定方法,试剂组成,测定试剂盒,分析装置及分析系统用于该方法
- 专利标题: Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method
- 专利标题(中): 血红蛋白衍生物测定方法,试剂组成,测定试剂盒,分析装置及分析系统用于该方法
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申请号: US11918394申请日: 2006-04-12
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公开(公告)号: US08921052B2公开(公告)日: 2014-12-30
- 发明人: Hirotaka Tanaka , Masanori Tanaka , Fumihisa Kitawaki
- 申请人: Hirotaka Tanaka , Masanori Tanaka , Fumihisa Kitawaki
- 申请人地址: JP Ehime
- 专利权人: Panasonic Healthcare Co., Ltd.
- 当前专利权人: Panasonic Healthcare Co., Ltd.
- 当前专利权人地址: JP Ehime
- 代理机构: Steptoe & Johnson LLP
- 优先权: JP2005-116870 20050414
- 国际申请: PCT/JP2006/307781 WO 20060412
- 国际公布: WO2006/112339 WO 20061026
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; C12M1/00 ; G01N33/72
摘要:
A sample solution including blood components is processed with a denaturalization reagent comprising a nonionic surface-activating agent and an oxidizing agent to denaturalize a hemoglobin derivative in the sample solution, and thereafter, an immunoassay is performing utilizing an antibody that is specific to a denaturalized site of the hemoglobin derivative to measure the amount of the hemoglobin derivative in the sample. Therefore, when performing assay of hemoglobin derivative, denaturalization of hemoglobin can be performed speedily and reliably while minimizing adverse effects of the denaturalization reagent on immune reaction.
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