Invention Grant
US08921569B2 Rationally improved isoniazid and ethionamide derivatives and activity through selective isotopic substitution
有权
通过选择性同位素替代，合理改善异烟肼和乙硫异烟酰胺衍生物和活性
- Patent Title: Rationally improved isoniazid and ethionamide derivatives and activity through selective isotopic substitution
- Patent Title (中): 通过选择性同位素替代，合理改善异烟肼和乙硫异烟酰胺衍生物和活性
-
Application No.: US13760605Application Date: 2013-02-06
-
Publication No.: US08921569B2Publication Date: 2014-12-30
- Inventor: Graham Timmins , Sharon Master , Vojo P Deretic , William Bishai
- Applicant: STC.UNM , Johns Hopkins University
- Applicant Address: US NM Albuquerque US MD Baltimore
- Assignee: STC.UNM,The Johns Hopkins University
- Current Assignee: STC.UNM,The Johns Hopkins University
- Current Assignee Address: US NM Albuquerque US MD Baltimore
- Agent Henry D. Coleman; R. Neil Sudol
- Main IPC: C07D213/86
- IPC: C07D213/86 ; A61K9/00 ; C07D213/81 ; C07D213/83 ; A61K31/44 ; A61K31/4409
Abstract:
The present invention relates to the use of isotopically labeled derivatives of isoniazid, ethionamide and related compounds as effective therapy for the treatment of mycobacterial diseases, including Mycobacterium tuberculosis.
Public/Granted literature
Information query
IPC分类:
