发明授权
US08933101B2 Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists 有权
Thia(dia)zoles作为快速解离的多巴胺2受体拮抗剂

Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
摘要:
The present invention relates to [1-(benzyl)-piperidin-4-yl]-([1,3,4]thiadiazol-2-yl)-amine and [1-(benzyl)-piperidin-4-yl]-(thiazol-2-yl)-amine derivatives of formula (I) that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.
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