发明授权
- 专利标题： Gamma secretase inhibitors
- 专利标题（中）： γ分泌酶抑制剂
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申请号： US14009418申请日： 2012-04-04
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公开(公告)号： US08933116B2公开(公告)日： 2015-01-13
- 发明人: Wen-Lian Wu , Duane A. Burnett , William J. Greenlee
- 申请人： Wen-Lian Wu , Duane A. Burnett , William J. Greenlee
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 J. Eric Thies; John C. Todaro
- 国际申请： PCT/US2012/032039 WO 20120404
- 国际公布： WO2012/138678 WO 20121011
- 主分类号： A61K31/352
- IPC分类号： A61K31/352 ; C07D493/06 ; A61K31/5377 ; A61K45/06 ; A61K31/453 ; C07D493/04 ; A61K31/35 ; A61K31/4178 ; A61K31/496 ; A61K31/397 ; A61K31/665 ; A61K31/4025 ; A61K31/422
摘要：
Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and use of the compound in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease.
公开/授权文献
- US20140018342A1 GAMMA SECRETASE INHIBITORS 公开/授权日：2014-01-16