发明授权
- 专利标题: Pyrazolo[1,5-a]pyrimidines useful as JAK2 inhibitors
- 专利标题(中): 吡唑并[1,5-a]嘧啶可用作JAK2抑制剂
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申请号: US12817785申请日: 2010-06-17
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公开(公告)号: US08937064B2公开(公告)日: 2015-01-20
- 发明人: Mark Ledeboer , Valerie Marone , Michelle Stewart , David Messersmith , John Duffy , Gabriel Martinez Botella , Jon Come , Huai Gao , Albert Pierce , Francesco Salituro
- 申请人: Mark Ledeboer , Valerie Marone , Michelle Stewart , David Messersmith , John Duffy , Gabriel Martinez Botella , Jon Come , Huai Gao , Albert Pierce , Francesco Salituro
- 申请人地址: US MA Boston
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: US MA Boston
- 代理商 Booyong S. Lim
- 主分类号: A61K31/535
- IPC分类号: A61K31/535 ; C07D415/00 ; C07D487/00 ; A01N43/90 ; C07D487/04
摘要:
The present invention relates to compounds of formula (I) useful as selective inhibitors of JAK2 kinase. The invention also provides pharmaceutical acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions or disorders. The invention also provides processes for preparing the compounds of the invention.
公开/授权文献
- US20110118255A1 PYRAZOLO[1,5-a]PYRIMIDINES USEFUL AS JAK2 INHIBITORS 公开/授权日:2011-05-19
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