- 专利标题： Expanding the eukaryotic genetic code
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申请号： US13329202申请日： 2011-12-16
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公开(公告)号： US08945926B2公开(公告)日： 2015-02-03
- 发明人: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- 申请人： Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- 申请人地址： US CA La Jolla
- 专利权人： The Scripps Research Institute
- 当前专利权人： The Scripps Research Institute
- 当前专利权人地址： US CA La Jolla
- 代理机构： Quine Intellectual Property Law Group P.C
- 代理商 Joan C. Harland
- 主分类号： C12N15/67
- IPC分类号： C12N15/67 ; A61K38/17 ; C12N9/00
摘要：
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献
- US20120253026A1 Expanding the Eukaryotic Genetic Code 公开/授权日：2012-10-04
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