发明授权
US08946179B2 Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
有权
用于调节小非编码RNA的低聚化合物和组合物
- 专利标题: Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
- 专利标题(中): 用于调节小非编码RNA的低聚化合物和组合物
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申请号: US13412307申请日: 2012-03-05
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公开(公告)号: US08946179B2公开(公告)日: 2015-02-03
- 发明人: C. Frank Bennett , Susan M. Freier , Richard H. Griffey
- 申请人: C. Frank Bennett , Susan M. Freier , Richard H. Griffey
- 申请人地址: US CA San Diego
- 专利权人: Regulus Therapeutics, Inc.
- 当前专利权人: Regulus Therapeutics, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: Casimir Jones, S.C.
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; C12N15/11
摘要:
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.
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