发明授权
- 专利标题: 3,4-diarylpyrazoles as protein kinase inhibitors
- 专利标题(中): 3,4-二芳基吡唑作为蛋白激酶抑制剂
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申请号: US13970854申请日: 2013-08-20
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公开(公告)号: US08946250B2公开(公告)日: 2015-02-03
- 发明人: Maurizio Pulici , Fabio Zuccotto , Gabriella Traquandi , Sonia Biondaro , Paolo Trifiro′ , Alessandra Badari , Stefano Nuvoloni , Giovanni Cervi , Chiara Marchionni , Michele Modugno
- 申请人: Maurizio Pulici , Fabio Zuccotto , Gabriella Traquandi , Sonia Biondaro , Paolo Trifiro′ , Alessandra Badari , Stefano Nuvoloni , Giovanni Cervi , Chiara Marchionni , Michele Modugno
- 申请人地址: IT Nerviano (MI)
- 专利权人: Nerviano Medical Sciences S.R.L.
- 当前专利权人: Nerviano Medical Sciences S.R.L.
- 当前专利权人地址: IT Nerviano (MI)
- 代理机构: Brinks Gilson & Lione
- 优先权: EP08161076 20080724
- 主分类号: A01N43/54
- IPC分类号: A01N43/54 ; A61K31/505 ; A01N43/40 ; A61K31/44 ; C07D239/02 ; C07D401/00 ; C07D401/04 ; C07D403/04 ; C07D407/14 ; C07D409/14 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; A61K31/506 ; A61K31/635 ; A61K45/06 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D513/14
摘要:
3,4-diarylpyrazole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
公开/授权文献
- US20140005150A1 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS 公开/授权日:2014-01-02