发明授权
- 专利标题: Zwitterionic lipids
- 专利标题(中): 两性离子脂质
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申请号: US13816882申请日: 2011-08-15
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公开(公告)号: US08956646B2公开(公告)日: 2015-02-17
- 发明人: Francis C. Szoka, Jr. , Colin Walsh , Vincent Venditto , Juliane Nguyen , Emily Perttu
- 申请人: Francis C. Szoka, Jr. , Colin Walsh , Vincent Venditto , Juliane Nguyen , Emily Perttu
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 代理机构: Morgan, Lewis & Bockius LLP
- 代理商 Jeffry S. Mann
- 国际申请: PCT/US2011/047780 WO 20110815
- 国际公布: WO2012/024233 WO 20120223
- 主分类号: C07C229/00
- IPC分类号: C07C229/00 ; C07C229/12 ; A61K9/127 ; C07C279/14 ; C07C309/14 ; C07F9/09 ; C07F9/54 ; C07F9/6509 ; C07J9/00 ; C40B40/04 ; A61K47/18 ; A61K47/28 ; C07J41/00
摘要:
In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.
公开/授权文献
- US20130216607A1 ZWITTERIONIC LIPIDS 公开/授权日:2013-08-22
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