发明授权
- 专利标题: Use of quinolinone derivatives as a research tool
- 专利标题(中): 使用喹啉酮衍生物作为研究工具
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申请号: US13885098申请日: 2011-11-15
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公开(公告)号: US08957091B2公开(公告)日: 2015-02-17
- 发明人: Martial Ruat , Helene Faure , Tatiana Gorojankina
- 申请人: Martial Ruat , Helene Faure , Tatiana Gorojankina
- 申请人地址: FR Paris
- 专利权人: Centre National de la Recherche Scientifique
- 当前专利权人: Centre National de la Recherche Scientifique
- 当前专利权人地址: FR Paris
- 代理机构: Alston & Bird LLP
- 优先权: FR1004444 20101116
- 国际申请: PCT/IB2011/055098 WO 20111115
- 国际公布: WO2012/066479 WO 20120524
- 主分类号: A61K31/04
- IPC分类号: A61K31/04 ; G01N33/68 ; G01N33/566 ; G01N33/50 ; G01N33/574
摘要:
The present invention relates to the use of quinolinone derivatives of general formula (I), ligands of the Smo receptor or of related receptors which target a binding site of the receptor which is different from the known ligand binding sites, as research tools for identifying modulators of the Smo receptor or of related receptors, characterizing the Hedgehog signalling pathway and diagnosis; the invention also relates to kits containing said derivatives of general formula (I).
公开/授权文献
- US20130236912A1 Use Of Quinolinone Derivatives As A Research Tool 公开/授权日:2013-09-12
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