发明授权
US08961994B2 DNA constructs eliciting immune response against flavivirus and effective adjuvants
有权
引发针对黄病毒和有效佐剂的免疫应答的DNA构建体
- 专利标题： DNA constructs eliciting immune response against flavivirus and effective adjuvants
- 专利标题（中）： 引发针对黄病毒和有效佐剂的免疫应答的DNA构建体
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申请号： US13129599申请日： 2009-11-17
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公开(公告)号： US08961994B2公开(公告)日： 2015-02-24
- 发明人: Mathura P. Ramanathan , Niranjan Y Sardesai
- 申请人： Mathura P. Ramanathan , Niranjan Y Sardesai
- 申请人地址： US PA Plymouth Meeting
- 专利权人： VGX Pharmaceuticals, LLC
- 当前专利权人： VGX Pharmaceuticals, LLC
- 当前专利权人地址： US PA Plymouth Meeting
- 代理商 Thomas Kim
- 国际申请： PCT/US2009/064726 WO 20091117
- 国际公布： WO2010/057159 WO 20100520
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; C12N15/40 ; C12N15/62 ; A61K39/00
摘要：
Aspects of the present invention relate to isolated nucleic acids that encode a consensus DIII domain of protein E and vaccines made using same, and also methods for using the aforementioned to generate in a host an immune response against multiple serotypes of flavivirus, particularly West Nile virus and Japanese encephalitis virus.
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