The present disclosure provides a global calibration method based on a rigid bar for a multi-sensor vision measurement system, comprising: step 1, executing the following procedure for at least nine times: placing, in front of two vision sensors to be calibrated, a rigid bar fasten with two targets respectively corresponding to the vision sensors; capturing images of the respective targets by their corresponding vision sensors; extracting coordinates of feature points of the respective targets in their corresponding images; and computing 3D coordinates of each feature points of the respective targets under their corresponding vision sensor coordinate frames; and Step 2, computing the transformation matrix between the two vision sensors, with the constraint of the fixed position relationship between the two targets. The present disclosure also provides a global calibration apparatus based on a rigid bar for a multi-sensor vision measurement system. Putting the present disclosure to use can increase the accuracy of the global calibration, and also be suitable for the calibration of the multi-sensor vision system in the extremely large working space, which enlarges the application range of the present disclosure.