发明授权
US08969088B2 Substrate mimicking intercellular lipids in stratum corneum and method of evaluating skin roughening using the same
有权
基质在角质层中模拟细胞间脂质和使用其评估皮肤粗糙化的方法
- 专利标题: Substrate mimicking intercellular lipids in stratum corneum and method of evaluating skin roughening using the same
- 专利标题(中): 基质在角质层中模拟细胞间脂质和使用其评估皮肤粗糙化的方法
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申请号: US12998985申请日: 2009-09-01
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公开(公告)号: US08969088B2公开(公告)日: 2015-03-03
- 发明人: Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
- 申请人: Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
- 申请人地址: JP Tokyo
- 专利权人: Shiseido Company, Ltd.
- 当前专利权人: Shiseido Company, Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Foley & Lardner LLP
- 优先权: JP2008-335319 20081226
- 国际申请: PCT/JP2009/065268 WO 20090901
- 国际公布: WO2010/073777 WO 20100701
- 主分类号: G01B21/30
- IPC分类号: G01B21/30 ; G01N33/92 ; C09K3/00
摘要:
A substrate mimicking intercellular lipids in stratum corneum consisting of a substrate and a lipid membrane formed on the substrate, wherein the lipid membrane is formed from ceramide, palmitic acid and cholesterol, and the ceramide, palmitic acid and cholesterol are present at a mass ratio of 20-70%:10-60%:20-40% (ceramide:palmitic acid:cholesterol).
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