发明授权
- 专利标题： Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products
- 专利标题（中）： 鞘内巴氯芬药物剂型具有较少的降解产物
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申请号： US12701342申请日： 2010-02-05
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公开(公告)号： US08969414B2公开(公告)日： 2015-03-03
- 发明人: John J. Foster , Angela S. Strantz
- 申请人： John J. Foster , Angela S. Strantz
- 申请人地址： US MO Hazelwood
- 专利权人： Mallinckrodt LLC
- 当前专利权人： Mallinckrodt LLC
- 当前专利权人地址： US MO Hazelwood
- 主分类号： A61K31/195
- IPC分类号： A61K31/195 ; A61K9/00
摘要：
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time. Also disclosed are methods for preparing such compositions.
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