Invention Grant
- Patent Title: Human anti-human influenza virus antibody
- Patent Title (中): 人类抗人流感病毒抗体
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Application No.: US13141998Application Date: 2009-12-24
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Publication No.: US08975378B2Publication Date: 2015-03-10
- Inventor: Kazuyoshi Ikuta , Ritsuko Koketsu , Yoshinobu Okuno , Mikihiro Yunoki , Shoji Ideno , Masatoshi Oshita , Motoki Kuhara , Masatoshi Momota
- Applicant: Kazuyoshi Ikuta , Ritsuko Koketsu , Yoshinobu Okuno , Mikihiro Yunoki , Shoji Ideno , Masatoshi Oshita , Motoki Kuhara , Masatoshi Momota
- Applicant Address: JP Osaka JP Osaka
- Assignee: Osaka University,The Research Foundation for Microbial Diseases of Osaka University
- Current Assignee: Osaka University,The Research Foundation for Microbial Diseases of Osaka University
- Current Assignee Address: JP Osaka JP Osaka
- Agency: Kilyk & Bowersox, P.L.L.C.
- Priority: JP2008-330425 20081225; JP2009-146832 20090619
- International Application: PCT/JP2009/007159 WO 20091224
- International Announcement: WO2010/073647 WO 20100701
- Main IPC: C07K16/10
- IPC: C07K16/10 ; C12N15/13 ; A61K39/00

Abstract:
Provided is a human antibody having a neutralization activity against a human influenza virus. More specifically, provided is a human antibody which recognizes a highly conserved region in a human influenza A virus subtype H3N2 or a human influenza B virus and has a neutralization activity against the virus. The human antibody is a human anti-human influenza virus antibody, which has a neutralization activity against a human influenza A virus subtype H3N2 and binds to a hemagglutinin HA1 region of the human influenza A virus subtype H3N2, or which has a neutralization activity against a human influenza B virus, and includes, as a base sequence of a DNA encoding a variable region of the antibody, a sequence set forth in any one of SEQ ID NOS: 5 to 12.
Public/Granted literature
- US20110319600A1 Human Anti-Human Influenza Virus Antibody Public/Granted day:2011-12-29
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