发明授权
- 专利标题： Nucleic acid detection system and method for detecting influenza
- 专利标题（中）： 核酸检测系统及流感检测方法
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申请号： US11894908申请日： 2007-08-22
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公开(公告)号： US08980561B1公开(公告)日： 2015-03-17
- 发明人: Hong Cai , Jian Song
- 申请人： Hong Cai , Jian Song
- 申请人地址： US NM Los Alamos
- 专利权人： Los Alamos National Security, LLC.
- 当前专利权人： Los Alamos National Security, LLC.
- 当前专利权人地址： US NM Los Alamos
- 代理机构： Peacock Myers, P.C.
- 代理商 Philip D. Askenazy
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34
摘要：
The invention provides a rapid, sensitive and specific nucleic acid detection system which utilizes isothermal nucleic acid amplification in combination with a lateral flow chromatographic device, or DNA dipstick, for DNA-hybridization detection. The system of the invention requires no complex instrumentation or electronic hardware, and provides a low cost nucleic acid detection system suitable for highly sensitive pathogen detection. Hybridization to single-stranded DNA amplification products using the system of the invention provides a sensitive and specific means by which assays can be multiplexed for the detection of multiple target sequences.
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