Invention Grant
US08980873B2 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt
有权
11-（2-吡咯烷-1-基 - 乙氧基）-14,19-二氧杂-5,7,26-三氮杂 - 四环[19.3.1.1（2,6）.1（8,12）]十七酸-1（ 25），2（26），3,5,8,10,12（27），16,21,23-十氢化柠檬酸盐
![11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt](/docs/US/2015-03-17/US08980873B2/abs.jpg.600x600.jpg)
- Patent Title: 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt
- Patent Title (中): 11-（2-吡咯烷-1-基 - 乙氧基）-14,19-二氧杂-5,7,26-三氮杂 - 四环[19.3.1.1（2,6）.1（8,12）]十七酸-1（ 25），2（26），3,5,8,10,12（27），16,21,23-十氢化柠檬酸盐
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Application No.: US13133297Application Date: 2009-12-09
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Publication No.: US08980873B2Publication Date: 2015-03-17
- Inventor: Brian Dymock , Cheng H. Lee , Anthony D. William
- Applicant: Brian Dymock , Cheng H. Lee , Anthony D. William
- Applicant Address: US WA Seattle
- Assignee: CTI Biopharma Corp.
- Current Assignee: CTI Biopharma Corp.
- Current Assignee Address: US WA Seattle
- Agency: Novak Druce Connolly Bove + Quigg LLP
- International Application: PCT/SG2009/000473 WO 20091209
- International Announcement: WO2010/068181 WO 20100617
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D201/10
![11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt](/abs-image/US/2015/03/17/US08980873B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to certain salts of a 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (Compound I) which have been found to have improved properties. In particular the present invention relates to the citrate salt of this compound. The invention also relates to pharmaceutical compositions containing the citrate salt and methods of use of the citrate salt in the treatment of certain medical conditions.
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