Invention Grant
US08980903B2 Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
有权
融合的吡啶，嘧啶和三嗪化合物作为细胞周期抑制剂
- Patent Title: Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
- Patent Title (中): 融合的吡啶，嘧啶和三嗪化合物作为细胞周期抑制剂
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Application No.: US14453842Application Date: 2014-08-07
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Publication No.: US08980903B2Publication Date: 2015-03-17
- Inventor: Richard V. Connors , Kang Dai , John Eksterowicz , Pingchen Fan , Benjamin Fisher , Jiasheng Fu , Kexue Li , Zhihong Li , Lawrence R. McGee , Rajiv Sharma , Xiaodong Wang , Dustin L. McMinn , Jeffrey T. Mihalic , Jeffrey Deignan
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D491/147 ; C07D471/14 ; C07D471/04 ; C07D487/14 ; C07D491/107 ; C07D498/10
Abstract:
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives.
Public/Granted literature
- US20140350244A1 FUSED PYRIDINE, PYRIMIDINE AND TRIAZINE COMPOUNDS AS CELL CYCLE INHIBITORS Public/Granted day:2014-11-27
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