Invention Grant
- Patent Title: HDAC inhibiting derivatives of camptothecin
- Patent Title (中): HDAC抑制喜树碱衍生物
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Application No.: US13977413Application Date: 2012-01-06
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Publication No.: US08980909B2Publication Date: 2015-03-17
- Inventor: Yi Chen , Yu Chen
- Applicant: Yi Chen , Yu Chen
- Applicant Address: US DE Wyoming
- Assignee: Crystal Biopharmaceutical LLC
- Current Assignee: Crystal Biopharmaceutical LLC
- Current Assignee Address: US DE Wyoming
- Agency: McCarter & English, LLP
- Agent Elizabeth A. Hanley, Esq.; Yu Lu
- International Application: PCT/US2012/020398 WO 20120106
- International Announcement: WO2012/096832 WO 20120719
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A01N43/42 ; C07D491/22 ; A61K31/4745 ; A61K31/496 ; A61K31/506 ; A61K31/695 ; A61K45/06 ; C07F7/10

Abstract:
The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R1, R2, and R3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
Public/Granted literature
- US20130281402A1 HDAC INHIBITING DERIVATIVES OF CAMPTOTHECIN Public/Granted day:2013-10-24
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