发明授权
US08986681B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl-tRNA synthetases
有权
与苏氨酰-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
- 专利标题: Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl-tRNA synthetases
- 专利标题(中): 与苏氨酰-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
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申请号: US13643750申请日: 2011-04-27
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公开(公告)号: US08986681B2公开(公告)日: 2015-03-24
- 发明人: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Wing-Sze Lo , Jeffry Dean Watkins , Cheryl L. Quinn , John D. Mendlein
- 申请人: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Wing-Sze Lo , Jeffry Dean Watkins , Cheryl L. Quinn , John D. Mendlein
- 申请人地址: US CA San Diego CN Hong Kong
- 专利权人: aTyr Pharma, Inc.,Pangu BioPharma Limited
- 当前专利权人: aTyr Pharma, Inc.,Pangu BioPharma Limited
- 当前专利权人地址: US CA San Diego CN Hong Kong
- 代理机构: Cooley LLP
- 国际申请: PCT/US2011/034207 WO 20110427
- 国际公布: WO2011/139801 WO 20111110
- 主分类号: C12N9/00
- IPC分类号: C12N9/00 ; A61K38/53 ; C07K16/40
摘要:
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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