Invention Grant
US08987456B2 3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
有权
含有3-吡啶甲酰胺的脾脏酪氨酸激酶(SYK)抑制剂
- Patent Title: 3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
- Patent Title (中): 含有3-吡啶甲酰胺的脾脏酪氨酸激酶(SYK)抑制剂
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Application No.: US14349563Application Date: 2012-10-01
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Publication No.: US08987456B2Publication Date: 2015-03-24
- Inventor: Michael D. Altman , Kaleen Konrad Childers , Anthony Donofrio , John Michael Ellis , Sandra Lee Knowles , Alan B. Northrup
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Catherine D. Fitch
- International Application: PCT/US2012/058218 WO 20121001
- International Announcement: WO2013/052393 WO 20130411
- Main IPC: C07D215/38
- IPC: C07D215/38 ; C07D401/12 ; C07D401/14 ; C07D405/14 ; A61K31/444 ; A61K31/4709

Abstract:
The invention provides certain 3-pyridyl carboxamide-containing compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
Public/Granted literature
- US20140303206A1 3-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors Public/Granted day:2014-10-09
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