发明授权
US08992975B2 Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
有权
包含羟考酮和对乙酰氨基酚的组合组合物用于快速发作和延长的止痛持续时间
- 专利标题: Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
- 专利标题(中): 包含羟考酮和对乙酰氨基酚的组合组合物用于快速发作和延长的止痛持续时间
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申请号: US14109052申请日: 2013-12-17
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公开(公告)号: US08992975B2公开(公告)日: 2015-03-31
- 发明人: Krishna R. Devarakonda , Michael J. Giuliani , Vishal K. Gupta , Ralph A. Heasley , Susan Shelby
- 申请人: Mallinckrodt LLC
- 申请人地址: US MO Hazelwood
- 专利权人: Mallinckrodt LLC
- 当前专利权人: Mallinckrodt LLC
- 当前专利权人地址: US MO Hazelwood
- 代理机构: Mayer Brown LLP
- 主分类号: A61K31/485
- IPC分类号: A61K31/485 ; A61K9/24 ; A61K31/167 ; A61K9/20
摘要:
The present disclosure provides an extended release pharmaceutical composition comprising oxycodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
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