Invention Grant
US08993772B2 Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates 有权
制备4-氨基-5-氟-3-卤代-6-(取代)吡啶甲酸盐的方法

Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates
Abstract:
4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation, nitrile hydrolysis, esterification, and transition metal assisted coupling.
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