Methods and apparatus for optimizing wireless network performance by incorporating platform configuration and use case information. In one exemplary scheme, a client device provides the wireless network with an indications of impacted operations based on the client device's platform configuration. The wireless network can adjust the radio link to the client device so as to best accommodate the impacted operation. In one embodiment, a client device that includes a 3×3 Wireless Local Area Network (WLAN) (or 4×4, 2×2, etc.) and Bluetooth (BT) module identifies a subset of modulation and coding schemes (MCS) that are preferred for operation. The client device provides the identified subset to the WLAN access point (AP). Responsively, the WLAN AP selects a MCS, such that the client device's overall performance remains at an acceptable level. In another embodiment, the server/client can adjust MCS and/or active antenna chains based on the noise floor (NF) level.