发明授权
- 专利标题: Bicyclic compounds as mPGES-1 inhibitors
- 专利标题(中): 双环化合物作为mPGES-1抑制剂
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申请号: US13761937申请日: 2013-02-07
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公开(公告)号: US09006257B2公开(公告)日: 2015-04-14
- 发明人: Laxmikant Atmaram Gharat , Abhisek Banerjee , Neelima Khairatkar-Joshi , Vidya Ganapati Kattige
- 申请人: Glenmark Pharmaceuticals S.A.
- 申请人地址: CH La Chaux-de-Fonds
- 专利权人: Glenmark Pharmaceuticals S.A.
- 当前专利权人: Glenmark Pharmaceuticals S.A.
- 当前专利权人地址: CH La Chaux-de-Fonds
- 代理机构: Blank Rome LLP
- 优先权: IN372/MUM/2012 20120209; IN1302/MUM/2012 20120424; IN2576/MUM/2012 20120905
- 主分类号: A01N43/54
- IPC分类号: A01N43/54 ; A61K31/517 ; C07D239/88 ; C07D215/233 ; C07D239/94 ; C07D401/12 ; C07D217/22 ; C07D217/24
摘要:
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
公开/授权文献
- US20130210844A1 BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS 公开/授权日:2013-08-15
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