Invention Grant
US09011929B2 Composition for inducing tissue regeneration by activating platelet-rich plasma (PRP)
有权
通过激活富血小板血浆(PRP)诱导组织再生的组合物
- Patent Title: Composition for inducing tissue regeneration by activating platelet-rich plasma (PRP)
- Patent Title (中): 通过激活富血小板血浆(PRP)诱导组织再生的组合物
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Application No.: US13502116Application Date: 2009-11-17
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Publication No.: US09011929B2Publication Date: 2015-04-21
- Inventor: Hyun-Shin Park , Ji-Chul Yu , Ju-Hee Park , Jang-Hoon Kim , Hun Kim , Sae-Bom Lee , Jae-Deog Jang , Cheong-Ho Jang
- Applicant: Hyun-Shin Park , Ji-Chul Yu , Ju-Hee Park , Jang-Hoon Kim , Hun Kim , Sae-Bom Lee , Jae-Deog Jang , Cheong-Ho Jang
- Applicant Address: KR Seoul
- Assignee: Sewon Cellontech Co., Ltd.
- Current Assignee: Sewon Cellontech Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Novick, Kim & Lee, PLLC
- Agent Jae Youn Kim
- Priority: KR10-2009-0101387 20091023
- International Application: PCT/KR2009/006745 WO 20091117
- International Announcement: WO2011/049263 WO 20110428
- Main IPC: A61K35/16
- IPC: A61K35/16 ; A61K38/39 ; A61L27/36 ; A61L27/24 ; A61L27/38

Abstract:
The present invention relates to a composition for cartilaginous tissue repair and to a production method therefor. The present invention comprises the steps of: (a) dissolving freeze-dried fibrinogen in an aprotinin solution; (b) dissolving freeze-dried thrombin in a stabilizing solution; (c) mixing an enriched collagen solution with thrombin and the stabilizing solution; and installing the fibrinogen solution (a) to one side of a dual kit and the solution (c) containing the collagen to the other side, and then mixing and injecting into damaged cartilaginous tissue. In the present invention, which is constituted as described above, biomaterials such as collagen and fibrin are mixed so as to allow damaged cartilaginous tissue to be repaired to a state allowing transplantation onto the tissue, and efficient regeneration is induced, thereby making it possible to reduce surgery-related stress on people and animals while inducing relatively rapid and efficient cartilage repair and regeneration.
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