发明授权
US09012631B2 1,3-oxazolidine-2-one-like compound, preparation method and uses thereof
有权
1,3-恶唑烷-2-酮样化合物，其制备方法和用途
- 专利标题： 1,3-oxazolidine-2-one-like compound, preparation method and uses thereof
- 专利标题（中）： 1,3-恶唑烷-2-酮样化合物，其制备方法和用途
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申请号： US14125944申请日： 2011-08-10
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公开(公告)号： US09012631B2公开(公告)日： 2015-04-21
- 发明人: Si-Qing Wang , Yong Deng , Zai-Xin Chen , Hui Zhang , Zhi-Pei San , Bai-Yang Mao , Zheng-Jun Xia , Long Jiang , Ming-Guang Zhang , Song Lin , Ming-Lin Wang
- 申请人： Si-Qing Wang , Yong Deng , Zai-Xin Chen , Hui Zhang , Zhi-Pei San , Bai-Yang Mao , Zheng-Jun Xia , Long Jiang , Ming-Guang Zhang , Song Lin , Ming-Lin Wang
- 申请人地址： CN CN CN
- 专利权人： Yabang Pharmaceutical Co., Ltd,Jiangsu Yabang Shengyuan Pharmaceutical Co., Ltd,Changzhou Yabang Pharmaceutical Co., Ltd
- 当前专利权人： Yabang Pharmaceutical Co., Ltd,Jiangsu Yabang Shengyuan Pharmaceutical Co., Ltd,Changzhou Yabang Pharmaceutical Co., Ltd
- 当前专利权人地址： CN CN CN
- 代理机构： Law Offices of Albert Wai-Kit Chan, PLLC
- 优先权： CN201110159445 20110615
- 国际申请： PCT/CN2011/078211 WO 20110810
- 国际公布： WO2012/171248 WO 20121220
- 主分类号： C07D263/20
- IPC分类号： C07D263/20
摘要：
This invention provides 1,3-oxazolidin-2-one compounds of formula I and their salts, their preparation methods, and use in the preparation of linezolid racemate and its optical isomer, which are used as oxazolidinone antibacterial agents. In the formula, R is H, hydroxyl, halogen, C1-C12 alkyl, C1-C12 alkoxy, nitro and carboxyl; and R can be placed at any position on the benzene rings; and the compound is a racemate or an optical isomer.
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